Somatostatin Analogs In Diagnostics And Therapy (medical Intelligence Unit (unnumbered))
by Marek Pawlikowski /
2007 / English / PDF
3.6 MB Download
Somatostatin is a peptide isolated originally from the hypothalamus
and considered as an inhibitor of growth hormone secretion.
However, further studies have shown that the peptide was
ubiquitously distributed and exerts a large spectrum of
physiological effects, mostly of an inhibitory nature. The very
short half-life of the native peptide limits its therapeutic
application. To overcome this limitation the long-lasting modified
molecules (analogs) of somatostatin were synthesized. The present
book provides comprehensive data on the application of somatostatin
analogs in diagnostics and treatment of diseases, mostly endocrine
disorders and cancers.
Somatostatin is a peptide isolated originally from the hypothalamus
and considered as an inhibitor of growth hormone secretion.
However, further studies have shown that the peptide was
ubiquitously distributed and exerts a large spectrum of
physiological effects, mostly of an inhibitory nature. The very
short half-life of the native peptide limits its therapeutic
application. To overcome this limitation the long-lasting modified
molecules (analogs) of somatostatin were synthesized. The present
book provides comprehensive data on the application of somatostatin
analogs in diagnostics and treatment of diseases, mostly endocrine
disorders and cancers.
