Mechanisms Of Atrial Arrhythmias: Insights From The Development Of A Biophysically Detailed Model Of The Human Atria (springer Theses)
by Michael A. Colman /
2013 / English / PDF
8.2 MB Download
This thesis describes the development of biophysically detailed
computer models of the human atria and torso to study the
underlying mechanisms of cardiac diseases, some of the most common
causes of morbidity and mortality. This is a cross-disciplinary
project, involving fundamentals of cardiac electrophysiology,
physics of excitable media, applied mathematics and high
performance scientific computing and visualisation. The author uses
computer models to provide insights into the underlying mechanisms
of the genesis of atrial fibrillation and develops novel techniques
for the monitoring of atrial tachycardia.
This thesis describes the development of biophysically detailed
computer models of the human atria and torso to study the
underlying mechanisms of cardiac diseases, some of the most common
causes of morbidity and mortality. This is a cross-disciplinary
project, involving fundamentals of cardiac electrophysiology,
physics of excitable media, applied mathematics and high
performance scientific computing and visualisation. The author uses
computer models to provide insights into the underlying mechanisms
of the genesis of atrial fibrillation and develops novel techniques
for the monitoring of atrial tachycardia.